About Viruses
What They Are
A virus is basically a tiny bundle of genetic material—either DNA or RNA—carried in a shell called the viral coat, or capsid, which is made up of bits of protein called capsomeres. Some viruses have an additional layer around this coat called an envelope. That's basically all there is to viruses. Viruses are strange things that straddle the fence between living and non-living. On the one hand, if they're floating around in the air or sitting on a doorknob, they're inert. They're about as alive as a rock. But if they come into contact with a suitable plant, animal or bacterial cell, they spring into action. They infect and take over the cell like pirates hijacking a ship.
What They Look Like
There are thousands of different viruses that come in a variety of shapes. Many are polyhedral, or multi-sided, a bit like a cut gem. Other viruses are shaped like spiky ovals or bricks with rounded corners. Some are like skinny sticks while others look like bits of looped string. Some are more complex and shaped like little lunar landing pods.
Where They're Found
Viruses are found on or in just about every material and environment on Earth from soil to water to air. They're basically found anywhere there are cells to infect. Viruses have evolved to infect every form of life, from animal to plant and from fungi to bacteria. However, viruses tend to be somewhat picky about what type of cells they infect. Plant viruses are not equipped to infect animal cells, for example, though a certain plant virus could infect a number of related plants. Sometimes, a virus may infect one creature and do no harm, but cause havoc when it gets into a different but closely enough related creature. For example, the Hantavirus is carried by deer mice without much noticeable effect on the rodents. But if Hantavirus gets into a person, it causes a dramatic and frequently deadly disease marked by excessive bleeding.
Single-Minded Mission
Viruses exist for one purpose only: to reproduce. To do that, they have to take over the reproductive machinery of suitable host cells.
Upon landing on an appropriate host cell, a virus gets its genetic material inside the cell either by tricking the host cell to pull it inside, like it would a nutrient molecule, or by fusing its viral coat with the host cell wall or membrane and releasing its genes inside. Some viruses inject their genes into the host cell, leaving their empty viral coats sitting outside.
If a virus is a DNA virus, its genetic material then inserts itself into the host cell's DNA. If the virus is an RNA virus, it must first turn its RNA into DNA using the host cell's machinery before inserting into the host DNA. The viral genes are then copied many, many times, using the machinery the host cell would normally use to reproduce its own DNA. The virus uses the host cell's enzymes to build new viral capsids and other viral proteins. The new viral genes and proteins then come together and assemble into whole new viruses. The new viruses are either released from the host cell without destroying the cell or eventually build up to a large enough number that they burst the host cell like an overfilled water balloon.
How to destroy Viruses
Viruses aren't considered living organisms, but they are very dependent on living cells to replicate. The structure of the virus includes the envelope which is constituted by proteins and the genetic material which can be DNA or RNA. All these components are thermosensible. The genetic material and the proteins have complex structures that are involved in their function and the change of their arrangements may result in lost of function. This process is called denaturation. There are two basic ways to do that: changing pH and temperature.
The avian virus, H5N1, is a negative-sense, single-stranded RNA virus 5 , which has two types of proteins in its surface: hemagglutinin (HA) and neuraminidase (NA) 6 . It is known from the literature that the virus can be inactivated by 56 o C in 3 hours and 60 o C in 30 minutes 1 . Thus, only four degrees of temperature elevation reduced the time of inactivation exposure about 85%.
The swine flu H1N1 virus is a new strain of the H1N1 virus subtype of influenza A. All influenza A viruses contain hemagglutinin and neuraminidase, although the structure of these proteins differ from strain to strain due to rapid genetic mutation in the viral genome. Influenza A virus strains are assigned an H number and an N number based on which forms of these two proteins the strain contains. There are 16 H and 9 N subtypes known in birds, but only H 1, 2 and 3, and N 1 and 2 are commonly found in humans.
About the Author
Kunbi Balogun
AllergyMatters.com
Comments (0) 19.08.2009. 14:27
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